NEONATAL SCREENING FOR HYPOTHYROIDISM WITH T4 RIA

Neonatal screening for congenital hypothyroidism: primary thryotropin screening: comparison of false positive rate using radioimmunossay (RIA) Vs fluorometric assay (FIA)

Background In Indonesia one of the challenges in implementing neonatal screening for congenital hypothyroidism (CH) is early discharge of infants, therefore we could not avoid to take the specimens between 24 to 48 hours of age, resulted in high false-positive rate. Since the begining of the neonatal screening program, radioimmunoassay (RIA) was used for primary TSH screening. Fluoroimmunoassay...

Neonatal screening for congenital hypothyroidism in Pakistan.

Congenital hypothyroidism is a preventable cause of mental retardation. Since clinical signs of congenital hypothyroidism do not generally become obvious before three months of age, screening programmes have been introduced in North America and Europe, which consist of T4 or TSH screening on newborn infants on the third day of life. The screening for congenital hypothyroidism was initiated in P...

Confirming congenital hypothyroidism identified from neonatal screening.

All patients identified in the neonatal screening programme for congenital hypothyroidism in Northern Ireland between 1983 and 1993 were reviewed. 131 infants were recalled because of TSH elevation of whom 85 proved to have true permanent congenital hypothyroidism, while 44 had transient TSH elevation and 2 cases died before the diagnosis could be confirmed. TSH elevation at presentation was mi...

Audit of neonatal screening programme for phenylketonuria and congenital hypothyroidism.

The performance of the neonatal screening programme was audited against clinical standards in the Bath clinical area from 1 April 1994 to 31 March 1996. The standards and policy were agreed by local service provider representatives of the screening and were audited, using laboratory and child health computer systems and medical records. Two annual reports were produced with recommendations for ...

Economic evaluation of neonatal screening for phenylketonuria and congenital hypothyroidism